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Our mission

is to improve the standard of care for treatment of gastrointestinal bleeding and protection of the mucosa in endoscopy procedures.


We are developing GastroShield, an advanced biocompatible material for effective management of gastrointestinal bleeding and shielding of high-risk lesions.

Instant hemostasis

Activates immediately upon application.

Durable

Barrier remains adhered in place during the healing process.

Protective Barrier

Strong and flexible shield provides effective bleed management.

Transparent

Preserves visualization of the lesion.

The Problem:
GI hemorrhage alone results in

+500,000

hospital admissions

+2 MILLION

hospital days

$5 BILLION

in direct costs

11,000

in-hospital deaths.

Despite advances in endoscopy, controlling GI bleeding and protecting large lesions remains challenging.

  • Powder hemostats can cloud visualization, clog catheters, and wash away quickly—increasing rebleeding and the need for additional interventions

  • Powders provide transient coating, while standard clips struggle with large or irregular lesions.

  • Procedure inefficiencies — Poor bleeding control drives added interventions and repeat visits—more cost for hospitals, more delays for patients.

Our Technology

1. Built on a Decade of Materials Science Research at MIT

GastroShield is founded on more than ten years of materials science and tissue engineering research at MIT. Our team has developed advanced hydrogel systems designed for challenging environment.

> SEE PUBLICATIONS

2. Instant Adhesion Through a Two-Component Hydrogel System

GastroShield is delivered as two liquid components that mix at the tip of an endoscopic catheter. Upon contact with GI tissue, they rapidly form a thin, durable hydrogel layer that adheres strongly—even in the presence of blood, moisture, or constant motion.

> SEE CHEMISTRY SCHEME

3. Targeted, Transparent,
Durable Protection

The hydrogel forms a transparent coating that preserves visualization of the underlying tissue. Its mechanical strength and tunable degradation profile provide extended protection where powders and short-lived gels often fail to remain effective.

> SEE VIDEO

Meet the Team

OUR Support and Partners